Aloe vera is relatively easy to care for in cultivation in frost-free climates. The species requires well-drained sandy potting soil in moderate light. If planted in pot or other containers ensure sufficient drainage with drainage holes. The use of a good quality commercial potting mix to which extra perlite, granite grit, or coarse sand are added is recommended. Alternatively, pre-packaged 'cacti and succulent mixes' may also be used. Potted plants should be allowed to completely dry prior to re-watering. During winter, A. vera may become dormant, during which little moisture is required. In areas that receive frost or snow the species is best kept indoors or in heated glasshouses.

A. vera has a long history of cultivation throughout the drier tropical and subtropical regions of the world, both as an ornamental plant and for herbal medicine. For its herbal and medicinal uses, many of which are shared with related species, see Aloe.

Usage

A. vera has been used externally to treat various skin conditions such as cuts, burns and eczema. It is alleged that sap from Aloe vera eases pain and reduces inflammation. Evidence on the effects of A. vera sap on wound healing, however, is contradictory (Vogler and Ernst, 1999). A study performed in the 1990s showed that the healing time of a moderate to severe burn was reduced when the wound was treated on a regular basis with Aloe vera gel, compared to the healing of the wound covered in a gauze bandage (Farrar, 2005). In contrast, another study suggested wounds to which Aloe vera gel was applied were significantly slower to heal (Schmidt and Greenspoon, 1991).

A. vera's beneficial properties may be attributed to mucopolysaccharides present in the inner gel of the leaf, especially acemannan (acetylated mannans). An injectable form of acemannan manufactured and marketed by Carrington Laboratories as Acemannan Immunostimulant™ has been approved in the USA for treatment of fibrosarcoma (a type of cancer) in dogs and cats after clinical trials. It has not been approved for use by humans, and although it is not a drug its sale is controlled and it can only be obtained through a veterinary doctor.

Cosmetic companies add sap or other derivatives from A. vera to products such as makeup, moisturisers, soaps, sunscreens, shampoos and lotions, though the effectiveness of Aloe vera in these produces remains unknown. A. vera gel is also alleged to be useful for dry skin conditions, especially eczema around the eyes and sensitive facial skin.

An article published in the British Journal of General Practice suggests that A. vera is effective at treating athlete's foot. The topical application of A. vera is not an effective preventative for radiation-induced injuries.

Whether or not it promotes wound healing is unknown, and even though there are some promising results, clinical effectiveness of oral or topical A. vera remains unclear at present.